CAS 2958-04-5: 2-{[(3alpha,5beta,6alpha)-3,6-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid

Taurohyodeoxycholic acid (THDCA) is a bile acid.THDCA reduces TNF-α and IL-6 and CD36 and up-regulating CYP7B1 and down-regulating CYP7A1 in HCC liver.

Applications A bile acid which stimulates the flow of bile salts, for potential treatment of Irritable Bile Syndrome. References Gnewuch, C., et al.: World J. Gastroenterol., 15, 3134 (2009), Yu, B., et al.: J. Nat. Prod., 72, 24 (2009), Lim, S., et al.: Int. J. Cancer, 126, 1582 (2010),

Applications Unlabeled Taurohyodeoxycholic Acid (T007900) is a bile acid which stimulates the flow of bile salts, for potential treatment of Irritable Bile Syndrome. References Gnewuch, C., et al.: World J. Gastroenterol., 15, 3134 (2009), Yu, B., et al.: J. Nat. Prod., 72, 24 (2009), Lim, S., et al.: Int. J. Cancer, 126, 1582 (2010),

Taurohyodeoxycholic acid (THDCA) is a bile acid that is used for the treatment of chronic inflammatory bowel disease. It is believed to work by reducing the production of pro-inflammatory cytokines, thereby reducing inflammation. THDCA has also been shown to inhibit the enzyme polymerase chain reaction, which may be useful in preventing infections caused by bacteria or viruses. It has been shown to have a positive effect on energy metabolism and cell lysis, as well as an antibody response and bowel disease. THDCA has been shown to have beneficial effects on hepatic steatosis and locomotor activity in experimental models.