CAS 29632-74-4: 2-Fluoro-4-iodoaniline

2-Fluoro-4-iodoaniline (2F4IA) is a chemical that belongs to the class of halogen compounds. This chemical has shown an ability to inhibit the growth of skin cancer cells in culture and may be used for the treatment of skin cancer. 2F4IA has been found to contain impurities, such as nitro, chloride, and coelomic tissue extract. The purity of this chemical was found to be constant using plasma mass spectrometry. 2F4IA is also a fluorine-containing compound that can bind amines and form conjugates with them.

2-Fluoro-4-iodoaniline

2-Fluoro-4-iodoaniline is widely used in the pharmaceutical, chemical and food industries as a fundamental building block to create a variety of important compounds. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications 2-Fluoro-4-iodoaniline is widely used in the pharmaceutical, chemical and food industries as a fundamental building block to create a variety of important compounds. 2-Fluoro-4-iodoaniline is mostly known as a moiety of TAK-733, a selective inhibitor of mitogen-activated or extracellular signal-regulated protein kinase kinase 2 (MEK2). References Dong, Q., et al.: Bioorg. Med. Chem. Lett., 21, 1315 (2011); Heald, R., et al.: J. Med. Chem., 55, 4594 (2012)