AVN-944, with the CAS number 297730-17-7, is a chemical compound that has garnered interest in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is classified as a small molecule inhibitor, specifically targeting certain enzymes involved in cellular processes. AVN-944 has been studied for its role in modulating pathways related to cancer and other diseases, showcasing its potential as an anti-cancer agent. The compound is characterized by its unique molecular structure, which includes specific functional groups that contribute to its biological activity. In preclinical studies, AVN-944 has demonstrated efficacy in inhibiting tumor growth and promoting apoptosis in cancer cells. Additionally, its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, are critical for determining its suitability for clinical use. Ongoing research aims to further elucidate its mechanism of action and optimize its therapeutic profile, making it a compound of interest in drug development.

AVN-944

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AVN-944 is a nucleotide analog that inhibits the synthesis of ATP in cells by interfering with DNA replication. AVN-944 has been shown to inhibit the growth of prostate cancer cells and myeloid leukemia cells, as well as suppressor genes in endothelial cells. The drug also has antiangiogenic properties by inhibiting endothelial cell proliferation. In addition, AVN-944 has been shown to have therapeutic potential for autoimmune diseases and cancer, including metastatic pancreatic cancer.

AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.

CAS 297730-17-7: AVN-944

AVN-944

Ref: 3D-XLA73017

AVN-944

Ref: 54-BUP07200

AVN-944

Ref: IN-DA00BF5K

AVN-944

Ref: TM-T1979