CAS 30163-82-7: 3-(2-methyl-1H-benzimidazol-1-yl)propanoic acid

3-(2-Methyl-1H-benzimidazol-1-yl)propanoic acid is a heterocyclic compound that has potential antimicrobial properties. It has been shown to have antimicrobial activity against bacteria and fungi, but not against viruses. 3-(2-Methyl-1H-benzimidazol-1-yl)propanoic acid is converted to the corresponding hydrazide by reaction with hydrazine hydrate in water at pH 3. The hydrazide reacts with acetoacetate or ethyl acetoacetate in a cyclocondensation reaction to form the corresponding semicarbazide. The semicarbazides can then be hydrolyzed to release the original amine or alkylated with an alkylating agent such as thiolactic acid, benzimidazole derivative, oxadiazole, or aldehyde.