
CAS 30220-46-3: Ingenol
Formula:C20H28O5
InChI:InChI=1S/C20H28O5/c1-9-7-19-10(2)5-13-14(18(13,3)4)12(17(19)24)6-11(8-21)16(23)20(19,25)15(9)22/h6-7,10,12-16,21-23,25H,5,8H2,1-4H3/t10-,12+,13-,14+,15+,16-,19+,20-/m1/s1
InChI key:InChIKey=VEBVPUXQAPLADL-POYOOMFHSA-N
SMILES:O[C@@]12[C@@]3(C(=O)[C@]([C@]4([C@@](C[C@H]3C)(C4(C)C)[H])[H])(C=C(CO)[C@H]1O)[H])C=C(C)[C@@H]2O
Synonyms:- (1aR,2S,5R,5aR,6S,8aS,10aR)-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one
- (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-Octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one
- (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one
- (1aR,5R,5aR,6S,9R,10aR)-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one
- 1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one, 1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-, (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-
- 1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one, 1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-, [1aR-(1aα,2β,5β,5aβ,6β,8aα,9α,10aα)]-
- 1aalpha,2alpha,5beta,5abeta,6beta,beta,9 alpha, 10,10aalpha-Octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1H-2,8aalpha-methano cyclopenta(a)cyclopropa(e)cyclodecen-11-one
- 5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one
- (-)-Ingenol
- Ingenol
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Found 11 products.
Ingenol
CAS:Controlled ProductApplications Ingenol, is the analogue of Ingenol 3-Angelate (I655800), which has anti-tumor activity when used topically for the treatment of actinic keratosis. References Ogbourne, S.M., et al.: Cancer. Res., 64, 2833 (2004); Zayed, S.M., et al.: J. Cancer. Res. Clin. Oncol., 127, 40 (2001);Formula:C20H28O5Color and Shape:NeatMolecular weight:348.431H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one,1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-, (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-
CAS:Formula:C20H28O5Purity:%Color and Shape:SolidMolecular weight:348.4333Ingenol
CAS:Ingenol is a natural product, which belongs to the group of ingenol esters. It has been shown to have significant cytotoxic effects on solid tumours in vitro and in vivo. Ingenol is metabolized by esterases and glucuronidases, or hydrolyzed by esterases or glucuronidases, leading to the release of methyl ethyl erythritol tetranitrate (MEETN). The MEETN molecule is then converted into a nitrate radical that causes cell death. Ingenol is also effective against skin cancers. Studies have shown that it inhibits the growth of skin cancer cells through mitochondrial membrane potential and cytosolic calcium levels. This drug has a chemical stability of less than one week at room temperature.Formula:C20H28O5Purity:Min. 95%Color and Shape:SolidMolecular weight:348.43 g/molIngenol
CAS:Ingenol mebutate treats actinic keratosis, has anticancer properties, and may reactivate latent HIV.Formula:C20H28O5Purity:99.78% - 99.87%Color and Shape:SolidMolecular weight:348.43Ref: TM-T5S2017
1mg52.00€5mg95.00€10mg127.00€25mg246.00€50mg467.00€100mg640.00€500mg1,359.00€1mL*10mM (DMSO)96.00€Ingenol
CAS:M01922 - IngenolFormula:C20H28O5Purity:>98%Color and Shape:Solid, FilmMolecular weight:348.4389953613281Ingenol
CAS:Formula:C20H28O5Purity:>99.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:348.44