Chlorambucil is a synthetic alkylating agent primarily used in chemotherapy for the treatment of certain types of cancer, particularly chronic lymphocytic leukemia and lymphoma. It belongs to the class of nitrogen mustards and functions by interfering with DNA replication, ultimately leading to cell death. Chlorambucil is characterized by its ability to form covalent bonds with DNA, which disrupts the normal cellular processes. The compound is typically administered orally and is known for its relatively mild side effect profile compared to other chemotherapeutic agents, although it can still cause bone marrow suppression and gastrointestinal disturbances. Its chemical structure includes a chloroethyl group, which is essential for its alkylating activity. Chlorambucil is classified as a hazardous substance, requiring careful handling and monitoring during use. Due to its mechanism of action, it is also associated with potential long-term risks, including secondary malignancies. Overall, Chlorambucil remains an important therapeutic option in oncology, particularly for patients who may not tolerate more aggressive treatments.

Chlorambucil

305-03-3: 4-(P-Bis(2-Chloroethyl)Aminophenyl)Butyric Acid, 4-(P-Bis(Beta-Chloroethyl)Aminophenyl)Butyric Acid, 4-(p-(N,N-Di-2-chloroethyl)aminophenyl)butyric acid, 4-(p-N,N-Di-(beta-chloroethyl)aminophenyl)butyric acid, 4-[4-[3-Chloro-1-(2-Chloroethyl)Propyl]Phenyl]Butanoic Acid, 4-[Bis(2-Chloroethyl)Amino]Benzenebutanoic Acid, 4-[Bis(2-chloroethyl)aminophenyl]butyric acid, 4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric acid, 4-{4-[Bis(2-Chloroethyl)Amino]Phenyl}Butanoic Acid, Ambochlorin, Amboclorin, Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-, Butanoic acid, 4-[bis(2-chloroethyl)amino]benzene, Butyric acid, 4-[p-[bis(2-chloroethyl)amino]phenyl]-, Cb 1348, Cb l348, Chloraminophen, Chloraminophene, Chlorbutin, Chloroambucil, Chlorobutin, Chlorobutine, Clorambucilo, Ecloril, Elcoril, Gamma-(P-Bis(2-Chloroethyl)Aminophenyl)Butyric Acid, Leukeran, Leukeran Tablets, Leukersan, Leukoran, Linfolizin, Linfolysin, Lympholysin, N,N-Di-(2-chloroethyl)-gamma-(p-aminophenyl)butyric acid, Nci 3088, Nsc 3088, Phenylbutyric acid nitrogen mustard, γ-[p-Bis(2-chloroethyl)aminophenyl]butyric acid, γ-[p-Di(2-chloroethyl)aminophenyl]butyric acid

CAS 305-03-3: Chlorambucil

Chlorambucil

Ref: TR-LGCFOR0821.00