The chemical substance known as Benzoic acid, 4-[5-[(2-ethoxy-5-pyrimidinyl)methyl]-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]-, ethyl ester, with CAS number 306974-70-9, is a complex organic compound characterized by its multi-functional structure. It features a benzoic acid moiety, which is known for its role in various biochemical applications, particularly as a preservative and in the synthesis of other organic compounds. The presence of a pyrimidine ring indicates potential biological activity, as pyrimidines are often found in nucleic acids and pharmaceuticals. The ethyl ester group suggests that the compound may exhibit improved solubility and bioavailability compared to its acid form. Additionally, the incorporation of a fluorophenyl group may enhance its pharmacological properties, potentially influencing its interaction with biological targets. Overall, this compound's intricate structure implies a range of potential applications in medicinal chemistry and drug development, warranting further investigation into its properties and effects.

Benzoic acid,4-[5-[(2-ethoxy-5-pyrimidinyl)methyl]-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]-,ethyl ester

306974-70-9: 1-(4-Ethoxycarbonylphenyl)-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone, Gw 1100

GW-1100 is a selective GPR40 and FFAR1 antagonist for the study of diabetes and metabolic diseases.

GW-1100

Please enquire for more information about 1-(4-Ethoxycarbonylphenyl)-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-(4-Ethoxycarbonylphenyl)-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone

Applications GW 1100 is a selective G protein-coupled receptor GPR40 antagonist. GW 1100 has been shown to reverse the effects GPR40 agonists which induce glucose-stimulated insulin secretion.
References Briscoe, C. et al.: Br. J. Pharmacol., 148, 619 (2006); Stoddart, L.A. et al.: Mol. Pharmacol., 71, 994 (2007);


CAS 306974-70-9: Benzoic acid,4-[5-[(2-ethoxy-5-pyrimidinyl)methyl]-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]-,ethyl ester

GW-1100

Ref: TM-T15448

1-(4-Ethoxycarbonylphenyl)-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone

Ref: 3D-FE102772

GW 1100

Ref: TR-G930200

GW-1100

Ref: IN-DA00BEB5