CAS 3093-35-4: Halcinonide
Formula:C24H32ClFO5
InChI:InChI=1S/C24H32ClFO5/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,26)17(28)11-22(16,4)24(19,31-20)18(29)12-25/h9,15-17,19,28H,5-8,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1
InChI key:InChIKey=MUQNGPZZQDCDFT-JNQJZLCISA-N
SMILES:C(CCl)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@](F)([C@@H](O)C3)[C@]5(C)C(CC4)=CC(=O)CC5)[H])[H]
Synonyms:- (11β,16α)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione
- (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (4bR,6bS,9aR,10aS)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (6bS,9aR)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- 21-Chloro-9-Alpha-Fluoro-11-Beta-Hydroxy-16-Alpha,17-Alpha-Isopropylidenedioxypregn-4-Ene-3,20-Dione
- 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv.
- Adcortin
- Alcinonide
- Halciderm
- Halcimat
- Halog
- See more synonyms
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Found 12 products.
GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
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Color and Shape:MixtureHalcinonide
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C24H32ClFO5Color and Shape:White to light yellow, PowderMolecular weight:454.96Halcinonide
CAS:Formula:C24H32ClFO5Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:454.96Halcinonide Hydroxide
CAS:Controlled ProductFormula:C24H32ClFO6Color and Shape:NeatMolecular weight:470.959Halcinonide
CAS:Halcinonide (Halciderm), a high-efficiency corticosteroid, is served as an anti-inflammatory agent used in topical preparations.Formula:C24H32ClFO5Purity:99.32% - 99.93%Color and Shape:SolidMolecular weight:454.96Ref: TM-T0107
1g567.00€10mg48.00€25mg65.00€50mg81.00€100mg131.00€200mg205.00€500mg373.00€1mL*10mM (DMSO)44.00€Pregn-4-ene-3,20-dione,21-chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,(11b,16a)-
CAS:Formula:C24H32ClFO5Purity:98%Color and Shape:SolidMolecular weight:454.9593Halcinonide
CAS:Halcinonide is a potent topical corticosteroid, which is a synthetically derived compound from hydrocortisone. It operates by penetrating the cell membranes and binding to cytoplasmic receptors, leading to a subsequent translocation to the nucleus where it modulates genetic expression. This action results in diminished synthesis of pro-inflammatory cytokines, thereby exerting strong anti-inflammatory, antipruritic, and vasoconstrictive effects. Halcinonide is primarily utilized for the management of various dermatological conditions characterized by inflammation and itching. It is effective against disorders such as eczema, psoriasis, and dermatitis, where control of the inflammatory response is crucial. Due to its potency, its use is reserved for conditions that do not respond adequately to less potent corticosteroids. Application involves a topical route, allowing for direct delivery to affected areas, minimizing systemic exposure. However, its use must be judiciously controlled to mitigate potential side effects such as skin atrophy or systemic absorption, especially in long-term treatment scenarios or under occlusive dressing. Thus, Halcinonide serves as an integral tool in the dermatological therapeutic arsenal.Formula:C24H32ClFO5Purity:Min. 95%Color and Shape:PowderMolecular weight:454.96 g/molHalcinonide
CAS:Halogenated derivatives of adrenal cortical hormonesFormula:C24H32ClFO5Color and Shape:White Off-White Crystalline PowderMolecular weight:454.19223
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