CAS: 311348-81-9

3-[(S)-{1-[2-(4-Fluorophenyl)Ethyl]-4-Piperidinyl}(Hydroxy)Methyl]-2-Methoxyphenol (EFDOH) is a chiral drug that has been shown to be effective in treating toxic epidermal necrolysis. This drug has been shown to inhibit voltage-dependent calcium channels and stimulate mitochondrial functions by increasing ATP production, which may be due to inhibition of hepatic enzymes. EFDOH also inhibits the synthesis of inflammatory mediators such as prostaglandin E2 and leukotriene B4, which can cause damage to skin cells. EFDOH is not metabolized by cytochrome p450 enzymes and does not have any clinically relevant interactions with other drugs. EFDOH is also stable in low doses and does not produce any liver impairment or histological changes in the liver.