CAS 31282-04-9: Hygromycin B
Formula:C20H37N3O13
InChI:InChI=1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6+,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20?/m1/s1
InChI key:InChIKey=GRRNUXAQVGOGFE-HUCHGKBZSA-N
SMILES:O[C@H]1C2(O[C@]3([C@@](O2)([C@@H](O)[C@@H](CO)O[C@H]3O[C@H]4[C@H](O)[C@@H](NC)C[C@@H](N)[C@@H]4O)[H])[H])O[C@]([C@H](CO)N)([C@H](O)[C@@H]1O)[H]
Synonyms:- (3'R,3aS,4S,4'R,5'R,6R,6'R,7S,7aS)-4-{[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy}-6'-[(1S)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)octahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-3',4',5',7-tetrol (non-preferred name)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-6-amino-6-deoxy-<smallcap>L</smallcap>-glycero-<smallcap>D</smallcap>-galacto-heptopyranosylidene-(1→2-3)-O-β-<smallcap>D</span>-talopyranosyl-(1→5)-2-deoxy-N<sup>3</sup>-methyl-
- Antihelmycin
- Hygromix 2.4
- Hygromix-8
- Hygromycin B
- Hygromycin B - Solution
- Hygromycin B Streptomyces hygroscopicus
- Hygromycin B solution Streptomyces hygroscopicus
- Hygrovetin
- Hygrovetine
- See more synonyms
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Found 18 products.
Hygromycin B
CAS:Hygromycin B binds near the A site of 16S rRNA and induces errors in the code by inhibition of translocation of peptydil-tRNA, however to a lesser extent compared to other aminoglycosides. Hygromycin B is efficient against bacteria, fungi and other eukaryotic cells, but more often used for the selection of eukaryotic cells including yeasts, such as, P. pastoris and S. cerevisiae, and mammalian cell lines, such as, CHO.Formula:C20H37N3O13Purity:Min. 95%Color and Shape:White PowderMolecular weight:527.52 g/molHygromycin B
CAS:Hygromycin B disrupts protein synthesis in 70S ribosomes, used as an anthelmintic in swine.Formula:C20H37N3O13Purity:98% - 99.78%Color and Shape:solidMolecular weight:527.52Hygromycin B
CAS:Formula:C20H37N3O13Purity:>80.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:527.52Hygromycin B (HGR), 90%
CAS:Formula:C20H37N3O13Purity:min. 90%Color and Shape:White to off - white, PowderMolecular weight:527.52Hygromycin B (HGR Solution), 50mg/ml in Aq. Solution
CAS:Formula:C20H37N3O13Color and Shape:Light yellow to very dark yellow to brown-yellow or light orange to very dark orange, Liquid, Clear to slight hazyMolecular weight:527.52Hygromycin B (HGR) for tissue culture, 90%
CAS:Formula:C20H37N3O13Purity:min. 90%Color and Shape:White to off white, PowderMolecular weight:527.52Hygromycin B Deuterated (d4 major)
CAS:Controlled ProductFormula:C20H33D4N3O13Color and Shape:NeatMolecular weight:531.54Hygromycin B, PBS solution
CAS:Hygromycin B, PBS solutionFormula:C20H37N3O13Purity:(hplc) min. 90.0% 91.5% (Typical Value in Batch COA)Color and Shape:LiquidMolecular weight:527.52g/molHygromycin B, powder
CAS:Hygromycin B, powderFormula:C20H37N3O13Purity:By hplc: 99.4% (Typical Value in Batch COA)Color and Shape: light tan powderMolecular weight:527.52g/molHygromycin B - min 90%
CAS:Inhibitor of protein synthesis; aminoglycosideFormula:C20H37N3O13Purity:Min. 90 Area-%Color and Shape:PowderMolecular weight:527.52 g/molHygromycin B
CAS:Controlled ProductApplications Hygromycin B is an aminoglycoside and a selective antibiotic agent for the hph gene. Hygromycin B inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Cha, T.S., et al.: World. J. Microbiol. Biotechnol., 28, 1771 (2012); Herrero, L., et al.: Biochem., 52, 171 (2013);Formula:C20H37N3O13Color and Shape:Off-WhiteMolecular weight:527.52Hygromycin B
CAS:An aminoglycoside antibiotic that kills bacteria by inhibiting protein synthesisHygromycin B is used for the selection and maintenance of prokaryotic and eukaryotic cells that contains the hygromycin resistance gene. This gene is frequently used as a selectable marker in research on plants. It stabilizes the transfer ribonucleic acid (tRNA)-ribosomal acceptor site, thereby inhibiting translocation. In addition to this, it serves as an aminoglycosidic antibiotic which inhibits protein synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C20H37N3O13Color and Shape:Cream to plale brown, PowderMolecular weight:527.52Hygromycin B, 50 mg/ml in distilled water, sterile-filtered
CAS:Hygromycin B was used for hygro resistance effect in the following cells transfected 293T cells with mixture of plasmids at 160 ?g/ml, MCF-7ALOX12 cells at 150 ?g/ml, MSCV Luciferase PGK-hygro plasmid and STAT3 Reporter HeLa Stable Cell Line (stably transfected with Luciferase gene under the control of STAT3 promoter) maintained in DMEM supplemented with 10% FBS. It is suitable for the selection of cells transfected with Escherichia coli hygromycin resistance gene (hyg or hph), as well as for the maintenance of the Hygromycin phenotype of resistant cells. Consistent with its more specific effect on translocation, hygromycin B exhibits monophasic inhibition of polypeptide synthesis, suggesting that it binds to a single site on the ribosome.This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C20H37N3O13Color and Shape:Liquid, Pale yellow to brownMolecular weight:527.52Hygromycin B
CAS:Formula:C20H37N3O13Purity:≥ 90.0%Color and Shape:White to beige powderMolecular weight:527.53
