CAS 314-40-9: Bromacil

Bromacil, a substituted uracil herbicide used worldwide, is not readily biodegradable and therefore has consequences to the environment.

Applications Bromacil is a compound used as an herbicide to control weeds in crop fields (such as pineapple fields). Bromacil is absorbed into the soil, and is utilized as the sole carbon source for soil microbes and degrades within 4 to 6 months of first application. This compound is a contaminant of emerging concern (CECs).Environmental toxin on US EPA Toxic Release Inventory list (TRI) list. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Gerstl, Z. & Yaron, B.: Soil Sci. Soc. Am. J., 47, 474 (1983); Leistra, M., et al.: Weed Res., 15, 243 (1975); Madhum, Y. & Freed, V.: Chemosphere, 16, 1003 (1987);

Bromacil is a herbicide that is used for wastewater treatment. It is also used to control the growth of bacteria in soil and water. Bromacil inhibits bacterial growth by binding cytoplasmic enzymes, especially those involved in fatty acid synthesis, and by inhibiting photosynthesis. Bromacil also has genotoxic effects on bacterial DNA, as demonstrated by an increase in the number of chromosomal aberrations observed in Escherichia coli cells incubated with bromacil. This compound binds to adenosine A3 receptors, which may be responsible for the inhibition of photosynthetic activity. The cytotoxicity of bromacil is not related to its ability to bind DNA but rather its ability to bind ribosomes and inhibit protein synthesis.