1-Pyrazin-2-ylthiourea is an organic compound characterized by its pyrazine ring structure, which is a six-membered aromatic ring containing two nitrogen atoms at the 1 and 4 positions. This compound features a thiourea functional group, which consists of a carbon atom double-bonded to sulfur and single-bonded to two amine groups. It is typically a white to off-white solid and is soluble in polar solvents such as water and alcohols. The presence of both the pyrazine and thiourea moieties contributes to its potential biological activity, making it of interest in medicinal chemistry and agricultural applications. 1-Pyrazin-2-ylthiourea may exhibit properties such as antimicrobial or antifungal activity, although specific biological effects can vary based on structural modifications and environmental conditions. As with many thiourea derivatives, it may also participate in various chemical reactions, including those involving nucleophilic substitution or coordination with metal ions. Proper handling and safety precautions are essential due to potential toxicity associated with thiourea compounds.

1-pyrazin-2-ylthiourea

31437-05-5: 1-(2-Pyrazinyl)thioharnstoff, 1-(2-Pyrazinyl)thiourea, thiourea, N-2-pyrazinyl-,  1-Pyrazin-2-ylthiourea

1-(Pyrazin-2-yl)thiourea

1-(Pyrazin-2-YL)Thiourea

N-Pyrazinylthiourea

Pyrazin-2-yl-thiourea is a complex molecule that binds to the active site of a drug target, stabilizing it. This process prevents it from binding to other molecules, which is required for the production of the target's biological effect. Pyrazin-2-yl-thiourea has shown antituberculosis activity in vitro and in vivo and has been found to be active against Mycobacterium tuberculosis strains. The antituberculosis activity of pyrazin-2-yl-thiourea may be due to its ability to inhibit the synthesis of RNA or protein in M. tuberculosis cells by binding to ribosomes or inhibiting RNA polymerase II activity.

CAS 31437-05-5: 1-pyrazin-2-ylthiourea

1-(Pyrazin-2-yl)thiourea

Ref: 10-F053857

1-(Pyrazin-2-YL)Thiourea

Ref: 54-OR1029184

N-Pyrazinylthiourea

Ref: IN-DA007JFE

Pyrazin-2-yl-thiourea

Ref: 3D-GBA43705