CAS 3144-09-0: Methanesulfonamide

Methanesulphonamide

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Methanesulfonamide is a drug that is used to treat infectious diseases and in the treatment of HIV. It is a non-steroidal anti-inflammatory drug that inhibits prostaglandin synthesis by blocking the activity of cyclooxygenase (COX) enzymes, COX-1 and COX-2. Methanesulfonamide has been shown to have chemoprotective effects against HIV infection and may reduce the risk of opportunistic infections associated with AIDS. Methanesulfonamide may also inhibit the production of inflammatory cytokines such as tumor necrosis factor alpha (TNFα) and interleukin-1β (IL-1β).

Applications Methanesulfonamide is used in biological studies to predict binding affinity and binding mode of protein ligand complexes. References Raha, K., et al.: J. Med. Chem., 48, 4558 (2005)

Methanesulfonamide will react with thionyl chloride, cyanates, carbon disulfide and ketones and aldehydes to prepare pharmaceuticals, brightening agent and other target molecules. It is also used in biological studies to predict binding affinity and binding mode of protein ligand complexes. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.