CAS: 317842-48-1

tert-Butyl (4-ethynylphenyl)carbamate

Tert-butyl N-(4-ethynylphenyl)carbamate is a new chemical compound that is synthesized by the Sharpless 1,3-dipolar cycloaddition reaction. This novel method can be used to introduce the tert-butyl group into peptides and proteins in an efficient manner. Tert-butyl N-(4-ethynylphenyl)carbamate has been shown to react with histidine residues on the surface of proteins and peptides, which can be used for introducing reactive groups or eliminating side chains. The introduction of such groups can be useful in protein engineering.