CAS 31949-21-0: 2-Bromo-1-(2-methoxyphenyl)ethanone

2-Bromo-2'-methoxyacetophenone is used as a pharmaceutical intermediate . This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Bromo-1-(2-methoxyphenyl)ethanone (2-BMEE) is an antibacterial agent that belongs to the benzofuran class of compounds. It has been shown to be a potent inhibitor against both Gram-positive and Gram-negative bacteria. 2-BMEE was first synthesized in 1958, and is still used as an antibacterial agent in some countries today. The synthesis of 2-BMEE involves two steps: 1) the synthesis of phenacyl bromide and 2) the quaternization of phenacyl bromide with dimethylamine. The crystallization process for this compound is efficient, and it can be produced in large quantities at a low cost. 2-BMEE inhibits bacterial growth by binding to the pyridinium ring of DNA gyrase, inhibiting DNA replication and transcription. This inhibition prevents the production of new proteins, causing cell death by apoptosis or nec

2-Methoxyphenacyl bromide

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.