CAS 321-38-0: 1-Fluoronaphthalene

Halogenated derivatives of aromatic hydrocarbons, nesoi

Fluoronaphthalene

1-Fluoronaphthalene is used in t-BuLi-mediated synthesis of 6-substituted phenanthridines. It is also used as a pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1-Fluoronaphthalene is a polyunsaturated compound that is used in analytical chemistry for the determination of test samples. It is an inhibitor of the enzyme IDO1, which plays an important role in the regulation of immune function, and has been shown to have anti-inflammatory properties. 1-Fluoronaphthalene can be synthesized by reacting n-dimethyl formamide with hydrogen fluoride and then adding a diazonium salt and hydrochloric acid. The UV absorption spectrum of 1-fluoronaphthalene displays a maximum at 248 nm. This compound binds to cation channels on cells, causing hyperpolarization.

Fluoronaphthalene is incompatible with strong oxidizing agents.

1-Fluoronaphthalene

Impurity Duloxetine EP Impurity G Applications 1-Fluoronaphthalene (Duloxetine EP Impurity G) is a fluorinated naphthalene derivative that is metabolized by fungal monooxygenase-epoxide hydrolase. Duloxetine (D721000) impurity. References Cerniglia, C.E. et al.: Appl. Env. Microbiol., 48, 294 (1984);