CAS 32328-03-3: Diethyl 3-hydroxyglutarate
Formula:C9H16O5
InChI:InChI=1S/C9H16O5/c1-3-13-8(11)5-7(10)6-9(12)14-4-2/h7,10H,3-6H2,1-2H3
InChI key:InChIKey=OLLQYIBTJXUEEX-UHFFFAOYSA-N
SMILES:C(CC(OCC)=O)(CC(OCC)=O)O
Synonyms:- 1,5-Diethyl 3-hydroxypentanedioate
- 3-Hydroxyglutaric acid diethyl ester
- Diethyl 3-hydroxypentanedioate
- Diethyl-Beta-Hydroxyglutarate
- Glutaric acid, 3-hydroxy-, diethyl ester
- NSC 62681
- Pentanedioic acid, 3-hydroxy-, 1,5-diethyl ester
- Pentanedioic acid, 3-hydroxy-, diethyl ester
- Diethyl-3-hydroxyglutarate
- Diethyl 3-hydroxyglutarate
Sort by
Found 5 products.
Diethyl 3-hydroxyglutarate
CAS:Diethyl 3-hydroxyglutarate is a chiral molecule that is used in the synthesis of pharmaceuticals. It has been shown to inhibit HMG-CoA reductase and is used as an inhibitor in drug development. Diethyl 3-hydroxyglutarate inhibits the enzyme HMG-CoA reductase, which catalyzes the conversion of HMG-CoA to mevalonic acid. This irreversible reaction provides the rate limiting step for cholesterol synthesis, and as such, inhibition of this enzyme leads to decreased levels of cholesterol in the body. The hydroxy group on diethyl 3-hydroxyglutarate can be deprotonated with a strong base such as LDA or LiHMDS to form an enolate anion that can react with electrophiles such as ketones or aldehydes to form keto esters or acetals. Diethyl 3-hydroxyglutarate also has lipase activity,Formula:C9H16O5Purity:Min. 95%Molecular weight:204.22 g/molDiethyl 3-hydroxyglutarate
CAS:Formula:C9H16O5Purity:95%Color and Shape:LiquidMolecular weight:204.2203Diethyl 3-Hydroxyglutarate
CAS:Formula:C9H16O5Purity:>95.0%(GC)Color and Shape:Colorless to Light yellow clear liquidMolecular weight:204.22
