CAS 3282-73-3: Didodecyldimethylammonium bromide

Applications Didodecyldimethylammonium Bromide

Didodecyldimethylammonium bromide (DDDAB) is a quaternary ammonium salt that acts as a p-gp substrate. It inhibits the growth of bacteria, such as Hl-60 cells, by binding to and blocking the efflux pump protein. DDDAB has been shown to be effective in the treatment of infectious diseases in animal models, including sepsis and pneumonia. It also inhibits the growth of bacteria by binding to metal hydroxides and metal ions, thereby inhibiting enzymatic activity. The biological properties of DDDAB are not fully understood but it has been shown that this drug can form disulfide bonds with other molecules and exhibits phase transition temperatures near room temperature. DDDAB also reacts with benzalkonium chloride and surfactants to form stable salts that have been shown to be effective for wastewater treatment.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Dilauryldimethylammonium bromide

(Di-n-dodecyl)dimethylammonium bromide is used as a phase transfer catalyst. It is also used as floor disinfectant. Further, it acts as surface-active agent. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.