3,4,5-Trimethoxybenzohydrazide is an organic compound characterized by its hydrazide functional group attached to a benzene ring that is substituted with three methoxy groups at the 3, 4, and 5 positions. This compound typically appears as a crystalline solid and is soluble in organic solvents due to its hydrophobic methoxy groups. The presence of the hydrazide functional group suggests potential reactivity, particularly in condensation reactions and as a precursor for various derivatives. Its structure may impart biological activity, making it of interest in pharmaceutical research. The compound is often synthesized through the reaction of 3,4,5-trimethoxybenzoic acid with hydrazine or its derivatives. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose risks if ingested or inhaled. Overall, 3,4,5-trimethoxybenzohydrazide is notable for its unique structural features and potential applications in organic synthesis and medicinal chemistry.

3,4,5-Trimethoxybenzohydrazide

3291-03-0: (3,4,5-Trimethoxybenzoyl)hydrazine, 3,4,5-Trimethoxybenzohydrazide, 3,4,5-Trimethoxybenzoic acid hydrazide, 3,4,5-Trimethoxybenzoic hydrazide, 3,4,5-Trimethoxybenzoylhydrazide, Benzoic acid, 3,4,5-trimethoxy-, hydrazide, NSC 39075

3,4,5-Trimethoxybenzhydrazide is an anticancer drug that belongs to the class of acylhydrazones. It has been shown to inhibit the proliferation of tumor cells and induce apoptosis by binding to pBR322 DNA. The molecular docking analysis revealed that this compound binds to nitrogen atoms with a dihedral angle of 180°. This binding results in the formation of a covalent bond between the amine group and the alpha carbon (C=N). 3,4,5-Trimethoxybenzhydrazide is also able to bind with serine protease and glibenclamide. This compound has been shown to have a high uptake rate and a reaction yield of 50%. It also has a viscosity value of 1.2 mPa·s at 25 °C.

CAS 3291-03-0: 3,4,5-Trimethoxybenzohydrazide

3,4,5-Trimethoxybenzhydrazide

Ref: 3D-FT38137

3,4,5-Trimethoxybenzohydrazide

Ref: IN-DA003IEW

3,4,5-Trimethoxybenzoic acid hydrazide

Ref: 10-F011241

3,4,5-Trimethoxybenzhydrazide

Ref: 54-OR4394