2-(4-Nitrophenyl)imidazo[1,2-a]pyridine, with the CAS number 3323-26-0, is a heterocyclic organic compound characterized by its imidazo and pyridine rings, along with a nitrophenyl substituent. This compound typically exhibits a pale yellow to orange crystalline appearance. It is known for its potential biological activity, particularly in medicinal chemistry, where it may serve as a scaffold for the development of pharmaceuticals. The presence of the nitro group can influence its electronic properties, making it a candidate for various chemical reactions, including nucleophilic substitutions and reductions. Additionally, the compound may exhibit fluorescence properties, which can be useful in analytical applications. Its solubility is generally moderate in organic solvents, and it may have limited solubility in water. Safety data should be consulted, as nitro compounds can pose health risks, including toxicity and environmental hazards. Overall, 2-(4-Nitrophenyl)imidazo[1,2-a]pyridine is of interest in both synthetic and applied chemistry contexts.

2-(4-Nitrophenyl)imidazo[1,2-a]pyridine

3323-26-0: 2-(4-Nitro-phenyl)-imidazo[1,2-a]pyridine, Imidazo[1,2-a]pyridine, 2-(4-nitrophenyl)-, Imidazo[1,2-a]pyridine, 2-(p-nitrophenyl)-, 2-(4-Nitrophenyl)imidazo[1,2-a]pyridine

2-(4-Nitrophenyl)imidazo[1,2-a]pyridine (NPI) is an orally active fluorescent probe for angiotensin II receptor type 1 (AT1). The fluorescence of NPI is quenched in the presence of AT1. Under conditions with high concentrations of AT1, the fluorescence of NPI changes from green to red. This property allows the measurement of AT1 levels in cells and tissues. In addition, NPI is a substrate for phenacyl choline esterase that catalyzes the hydrolysis of 2-(4-nitrophenyl)-imidazo[1,2-a]pyridine to 2-(4-nitrophenyl)-3-hydroxypyridine. The reaction time and temperature are dependent on the substrate concentration as well as pH and ionic strength. Reaction times increase with decreasing pH and increasing ionic strength.

CAS 3323-26-0: 2-(4-Nitrophenyl)imidazo[1,2-a]pyridine

2-(4-Nitrophenyl)imidazo[1,2-a]pyridine

Ref: 54-OR2105

2-(4-Nitrophenyl)imidazo[1,2-a]pyridine

Ref: 3D-FN131943

2-(4-Nitrophenyl)imidazo[1,2-a]pyridine

Ref: 10-F069228

8-(4-nitrophenyl)-1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraene

Ref: IN-DA00I6H6