BIX02188, with the CAS number 334949-59-6, is a small molecule that functions primarily as a chemical probe in biological research, particularly in the field of epigenetics. It is known for its role as a selective inhibitor of the protein lysine-specific demethylase 1 (LSD1), which is involved in the regulation of gene expression through histone modification. The inhibition of LSD1 by BIX02188 can lead to the modulation of various cellular processes, including differentiation and proliferation, making it a valuable tool for studying cancer biology and stem cell research. BIX02188 is characterized by its ability to selectively target LSD1 without significantly affecting other related enzymes, which is crucial for minimizing off-target effects in experimental settings. Its chemical structure includes specific functional groups that contribute to its binding affinity and selectivity. Overall, BIX02188 serves as an important compound for researchers investigating the epigenetic landscape and its implications in various diseases.

BIX02188

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Bix-02188 is a small molecule that inhibits protein synthesis by inhibiting the activity of the transcription-polymerase chain. Bix-02188 has been shown to have a protective effect on diabetic mice with chronic kidney disease. It also protects against renal damage caused by high salt and cancer, as well as lung damage caused by radical prostatectomy. The drug has been shown to inhibit the growth of cancer cells in culture and to reduce symptoms in patients with epidermal growth factor receptor mutations. Bix-02188 may also be used for the treatment of other diseases associated with uncontrolled cell proliferation, such as psoriasis and Alzheimer's disease.

Bix-02188

BIX02188 is a selective and potent MEK5 inhibitor that inhibits MEK5-induced apoptosis in cells expressing the oncogenic mutant FLT3-ITD.

CAS 334949-59-6: BIX02188

Bix-02188

Ref: 3D-JNA94959

BIX02188

Ref: TM-T1744

Bix-02188

Ref: IN-DA00C6F0

BIX02188

Ref: 54-BUP01716

Bix-02188

Ref: 54-BISN0195