Histidylprolineamide, with the CAS number 33605-69-5, is a dipeptide derivative composed of the amino acids histidine and proline, linked by a peptide bond. This compound is characterized by its unique structure, which includes an imidazole side chain from histidine that can participate in various biochemical interactions, and a pyrrolidine ring from proline that contributes to the molecule's conformational stability. Histidylprolineamide is known for its potential biological activities, including roles in peptide synthesis and as a building block in various biochemical pathways. It may exhibit properties such as antioxidant activity and involvement in cellular signaling processes. The compound is typically soluble in polar solvents, and its stability can be influenced by pH and temperature. As a research chemical, it is often studied for its implications in pharmacology and biochemistry, particularly in relation to its effects on protein structure and function.

Histidylprolineamide

33605-69-5: (2S)-1-[(2S)-2-Amino-3-(3H-imidazol-4-yl)propanoyl]pyrrolidine-2-carboxamide, His-pro-amide, L-histidyl-L-prolinamide

His-pro-amide is a reactive amide, which is an intermediate in the metabolic pathway of histidine. It can be formed by condensation of histidine with proline and amine groups. His-pro-amide is found in rat brain and has been shown to stimulate the release of thyrotropin. This compound also stimulates the release of hormones, such as corticosterone, from animals and has been shown to be effective in humans. His-pro-amide is not active as a substrate for hplc methods.

CAS 33605-69-5: Histidylprolineamide

Histidylprolineamide

Ref: 7W-GK8877

His-pro-amide

Ref: 3D-FH151509

L-Histidyl-L-prolinamide Ditrifluoroacetic Acid

Ref: TR-H456215