CAS 336113-53-2: Ispinesib
Formula:C30H33ClN4O2
InChI:InChI=1/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1
SMILES:CC(C)[C@H](c1nc2cc(ccc2c(=O)n1Cc1ccccc1)Cl)N(CCCN)C(=O)c1ccc(C)cc1
Synonyms:- Ispinesib (SB-715992 /CK0238273)
- N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxo-quinazolin-2-yl)-2-methyl-propyl]-4-methyl-benzamide
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Found 6 products.
Ispinesib
CAS:Inhibits mitotic kinesin spindle protein (KSP); antineoplasticFormula:C30H33ClN4O2Purity:Min. 95%Color and Shape:SolidMolecular weight:517.06 g/molIspinesib
CAS:Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplasticFormula:C30H33ClN4O2Purity:98% - 98.59%Color and Shape:SolidMolecular weight:517.06Ref: TM-T2103
1mg39.00€2mg50.00€5mg79.00€10mg118.00€25mg210.00€50mg339.00€100mg557.00€500mg1,216.00€1mL*10mM (DMSO)89.00€(R)-N-(3-Aminopropyl)-N-(1-(3-Benzyl-7-Chloro-4-Oxo-3,4-Dihydroquinazolin-2-Yl)-2-Methylpropyl)-4-Methylbenzamide
CAS:(R)-N-(3-Aminopropyl)-N-(1-(3-Benzyl-7-Chloro-4-Oxo-3,4-Dihydroquinazolin-2-Yl)-2-Methylpropyl)-4-MethylbenzamidePurity:98%Molecular weight:517.06g/molIspinesib
CAS:Controlled ProductApplications Ispinesib is the first potent, highly specific small-molecule inhibitor of KSP tested for the treatment of human disease. Anticancer agent. References Blangy, A., et al.: J. Biol. Chem., 272, 19418 (1997), Wood, K., et al.: Curr. Opin. Pharmacol., 1, 370 (2001), Sakowicz, R., et al.: Cancer Res., 64, 3276 (2004), Cochran, J., et al.: J. Biol. Chem., 280, 12658 (2005), Kapitein, L., et al.: Nature, 435, 114 (2005),Formula:C30H33ClN4O2Color and Shape:NeatMolecular weight:517.06
