CAS 33630-99-8: 3-Amino-2(1H)-pyridinone

It is used as pharmaceutical intermediate. It is involved in synthesis of functionalized pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives. The use of ethyl 2-chloro-3-oxopropanoate with 2-amino-3-hydroxypyridine or 3-amino-4-hydroxypyridine led, respectively, to imidazo[1,2-a]pyridine derivatives or ethyl pyrido[4,3-b][1,4] oxazine-2-carboxylate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

3-Amino-2-hydroxypyridine

3-Amino-2-hydroxypyridine is a heterocyclic compound that is reactive and putatively protonated. It has been shown to have inhibitory properties in cell culture. 3-Amino-2-hydroxypyridine can be activated by hydrochloric acid or trifluoroacetic acid. Hydrolysis of the amine group leads to the release of ammonia, which can be oxidized to form nitrous oxide. The photophysical properties of 3-amino-2-hydroxypyridine have been studied and found to be related to its amines and hydroxyl groups. Drug reactions are likely if it comes into contact with skin or mucous membranes.

3-Aminopyridin-2(1H)-one

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.