CAS 336881-26-6: Uridine,2'-deoxy-2'-fluoro-5-(trimethylstannyl)- (9CI)

2'-Deoxy-2'-fluoro-5-(trimethylstannyl)uridine-epimer is a novel nucleoside that is synthesized by the chemical reaction of 2'-deoxy-5-(trimethylstannyl)uridine and 5-bromo-2'-deoxyuridine. It is a nucleotide analogue that acts as a DNA phosphoramidite in solid phase synthesis. This compound has antiviral, anticancer, and antiviral properties. It can be used to activate ribonucleotides or deoxyribonucleotides for incorporation into DNA or RNA. 2'-Deoxy-2'-fluoro-5-(trimethylstannyl)uridine-epimer has shown good cytotoxicity against leukemia cells, lymphoma cells, and other tumor cells in vitro. This may be due to its ability to inhibit protein synthesis by blocking the enzyme ribonuclease H (RNase H