CAS 33745-47-0: Ethyl 3-formylbenzoate

Ethyl 3-formylbenzoate is a protease inhibitor that binds to the active site of the enzyme, thereby inhibiting its activity. It has been shown to inhibit proteases with high affinity and specificity. Ethyl 3-formylbenzoate interacts with other proteins such as streptavidin and can be used in experiments involving these proteins. Its interaction with hif-1α has been studied extensively, showing potent inhibition of this protein's activity. Hypoxia is induced by low oxygen concentrations, which leads to an increase in the expression of hypoxia inducible factor (HIF-1) protein. HIF-1α is a transcription factor that induces genes involved in cell survival when oxygen levels are low or absent. Ethyl 3-formylbenzoate inhibits HIF-1α and its downstream effects, including the induction of protease enzymes and their activities.