CAS 3385-03-3: Flunisolide

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Formula:C₂₄H₃₁FO₆

InChI:InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1

InChI key:InChIKey=XSFJVAJPIHIPKU-XWCQMRHXSA-N

SMILES:C(CO)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@]([C@@H](O)C3)([C@]5(C)C([C@@H](F)C4)=CC(=O)C=C5)[H])[H])[H]

Synonyms:

(6α,11β,16α)-6-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregna-1,4-diene-3,20-dione deriv.
6α-Fluoro-11β,21-dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
Aerobid
Aerobid M
Bronalide
Flunisolid
Flunisolida
Flunisolide
Lunis
Nasalide
Nasarel
Nisolid
Pregna-1,4-diene-3,20-dione, 6α-fluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
Rhinalar
Rs 3999
Soluzione
Synaclyn
Syntaris
UNII-78M02AA8KF
(6bS,9aR,12S)-12-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
Flunisolidum [INN-Latin]
Flunisolide [INN]
Flunisolide HFA
Aerospan
Pregna-1,4-diene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-
6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16, 17-acetal with acetone
(4aR,5S,6aS,6bS,9aR,10aS,10bS,12S)-12-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
Flunisolida [INN-Spanish]
Pregna-1,4-diene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11β,16α)-
Flunisolidum
Aerospan HFA
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS,12S)-12-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS,12S)-12-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one hydrate (2:1)
See more synonyms

Found 7 products.

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Flunisolide-d6
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3385-03-3
Formula:C₂₄₂H₆H₂₅FO₆
Color and Shape:Neat
Molecular weight:440.53
Ref: TR-F500487
250µg
293.00€
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2500µg
1,940.00€
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Flunie
CAS:
- 3385-03-3
Formula:C₂₄H₃₁FO₆
Molecular weight:434.50
Ref: 7W-GK1555
ne
To inquire
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Flunisolide
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3385-03-3
Flunisolide is a corticosteroid that relieves the symptoms of allergy, such as nasal congestion, sneezing, and runny nose. It also reduces levels of cortisol in the blood and may be used to treat asthma. Flunisolide is rapidly absorbed through the nasal mucosa and has been shown effective in vitro at inhibiting allergic reactions. Clinical trials have demonstrated long-term efficacy with flunisolide in the treatment of allergic rhinitis and asthma. Flunisolide has been shown to inhibit eosinophil cationic protein (ECP) synthesis and reduce airway hyperresponsiveness in asthmatic subjects. The chemical stability of flunisolide has been tested by exposing it to human serum for up to 24 hours at 37°C with no loss of activity. In addition, flunisolide does not cause skin irritation or local erythema on repeated topical applications to humans or animals. A two-way crossover study
Formula:C₂₄H₃₁FO₆
Purity:Min. 98 Area-%
Color and Shape:White Powder
Molecular weight:434.5 g/mol
Ref: 3D-FF23333
1g
483.00€
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2g
791.00€
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5g
1,807.00€
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10g
3,409.00€
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500mg
265.00€
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Flunisolide
CAS:
- 3385-03-3
Formula:C₂₄H₃₁FO₆
Purity:>98.0%(HPLC)
Color and Shape:White to Almost white powder to crystal
Molecular weight:434.50
Ref: 3B-F0437
1g
207.00€
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Flunisolide-d4 (major)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3385-03-3
Applications Flunisolide-d4 is the labeled analogue of Flunisolide (F500485), a synthetic fluorinated corticosteroid related to Prednisolone (P703740). Antiasthmatic. References Chu, N.I., et al.: Drug Metab. Dispos., 7, 81 (1979); Pakes, G.E., et al.: Drugs, 19, 397 (1980)
Formula:C₂₄D₄H₂₇FO₄
Color and Shape:Neat
Molecular weight:406.524
Ref: TR-F500489
1mg
274.00€
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10mg
1,722.00€
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Flunisolide
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3385-03-3
Applications Flunisolide is a synthetic fluorinated corticosteroid related to Prednisolone (P703740). Antiasthmatic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Chu, N.I., et al.: Drug Metab. Dispos., 7, 81 (1979), Pakes, G.E., et al.: Drugs, 19, 397 (1980)
Formula:C₂₄H₃₁FO₆
Color and Shape:White To Light Yellow
Molecular weight:887.01
Ref: TR-F500485
1mg
206.00€
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10mg
1,404.00€
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2500µg
400.00€
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Flunisolide
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 3385-03-3
Formula:C₂₄H₃₁FO₆
Color and Shape:Neat
Molecular weight:434.50
Ref: 04-C13726600
10mg
181.00€
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