CAS 340021-17-2: Tonapofylline
Formula:C22H32N4O4
InChI:InChI=1S/C22H32N4O4/c1-3-13-25-17-16(18(29)26(14-4-2)20(25)30)23-19(24-17)22-10-7-21(8-11-22,9-12-22)6-5-15(27)28/h3-14H2,1-2H3,(H,23,24)(H,27,28)
InChI key:InChIKey=ZWTVVWUOTJRXKM-UHFFFAOYSA-N
SMILES:C(CC(O)=O)C12CCC(CC1)(CC2)C3=NC4=C(N3)C(=O)N(CCC)C(=O)N4CCC
Synonyms:- Tonapofylline
- 4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)bicyclo[2.2.2]octane-1-propanoic acid
- BG 9928
- Bicyclo[2.2.2]octane-1-propanoic acid, 4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-
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Found 3 products.
Tonapofylline
CAS:Tonapofylline is a pharmaceutical preparation that is used to treat glomerular filtration rate problems and hepatic impairment. It is also used for the treatment of pulmonary edema caused by congestive heart failure, myocardial infarction, or cirrhosis. Tonapofylline inhibits the adenosine receptors in the lungs, which blocks the inhibitory effects of adenosine on the airways. This improves lung function and reduces pulmonary edema. Tonapofylline has also been shown to reduce levels of urea nitrogen and creatinine in patients with cirrhosis and cancer. Tonapofylline may also be used for cancer prevention because it lowers the risk of myocardial infarcts in patients with coronary artery disease or congestive heart failure.Formula:C22H32N4O4Purity:Min. 95%Molecular weight:416.5 g/molTonapofylline
CAS:Tonapofylline, orally active, selectively blocks A1 adenosine receptor (Ki: 7.4 nM), used in heart failure research.Formula:C22H32N4O4Purity:99.52%Color and Shape:SolidMolecular weight:416.51
