7-Fluoro-1H-indazole is a heterocyclic organic compound characterized by its indazole structure, which consists of a fused benzene and pyrazole ring. The presence of a fluorine atom at the 7-position of the indazole ring significantly influences its chemical properties, including its reactivity and potential biological activity. This compound is typically a solid at room temperature and is known for its moderate solubility in organic solvents. It may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry and drug development. The fluorine substituent can enhance lipophilicity and metabolic stability, which are desirable traits in pharmaceutical applications. Additionally, 7-Fluoro-1H-indazole can participate in various chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions, due to the presence of reactive sites on the indazole framework. Its unique structure and properties make it a valuable compound for research in both synthetic and medicinal chemistry.

7-Fluoro-1H-indazole

341-24-2: 1H-Indazole, 7-fluoro-, 7-fluoro-1H-indazole7-Fluoro Indazole

7-Fluoro indazole is a potent inhibitor of the enzyme cytochrome P450. It inhibits the activity of this enzyme by binding to the heme moiety, thus preventing electron transfer from NADPH to CYP450. 7-Fluoro indazole has been shown to interact with a number of other drugs, including amiodarone, cimetidine, clomiphene, dexamethasone, and erythromycin. 7-Fluoro indazole is an effective inhibitor of the human cytochrome P450 enzymes 1A2 and 2C9. The inhibition of these enzymes leads to decreased metabolism of certain drugs such as amiodarone or clomiphene. This drug also has inhibitory potencies against the human cytochrome P450 enzymes 3A4 and 2D6.

CAS 341-24-2: 7-Fluoro-1H-indazole

7-Fluoro-1H-indazole

Ref: 10-F076204

7-Fluoro-1H-indazole

Ref: 54-PC201233

7-Fluoro indazole

Ref: 3D-FF53854

7-Fluoro-1H-indazole

Ref: IN-DA003NF7