3-[(4-Methylpiperazin-1-yl)methyl]-5-nitro-1H-indole, with the CAS number 3414-71-9, is a chemical compound characterized by its indole core, which is a bicyclic structure consisting of a benzene ring fused to a pyrrole ring. The presence of a nitro group at the 5-position of the indole enhances its reactivity and potential biological activity. The compound features a 4-methylpiperazine moiety attached via a methylene bridge, which contributes to its pharmacological properties, particularly in medicinal chemistry. This piperazine derivative is often explored for its potential as a therapeutic agent, particularly in the context of neurological or psychiatric disorders, due to the piperazine's ability to interact with various neurotransmitter receptors. The compound's solubility, stability, and reactivity can be influenced by the functional groups present, making it a subject of interest in drug development and synthesis. Overall, its unique structure and functional groups suggest potential applications in pharmaceuticals and biochemistry.

3-[(4-methylpiperazin-1-yl)methyl]-5-nitro-1H-indole

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3-((4-Methylpiperazin-1-yl)methyl)-5-nitro-1H-indole is an inhibitor of bacterial replication. It binds to the active site of the enzyme DNA polymerase and prevents the addition of nucleotides to the growing strand of DNA. This results in cell death by preventing DNA synthesis. 3-(4-Methylpiperazin-1-yl)methyl)-5-nitro-1H indole has been shown to inhibit the growth of a number of bacteria, including Mycobacterium tuberculosis, Mycobacterium avium complex, and Clostridium perfringens. The compound was found to be effective as a fluorescence probe for monitoring DNA synthesis in living cells and has been used as a chemical inhibitor in enzymatic reactions.

CAS 3414-71-9: 3-[(4-methylpiperazin-1-yl)methyl]-5-nitro-1H-indole

3-((4-Methylpiperazin-1-yl)methyl)-5-nitro-1H-indole

Ref: 3D-DAA41471

3-((4-METHYLPIPERAZIN-1-YL)METHYL)-5-NITRO-1H-INDOLE

Ref: 10-F471231