CAS 34157-83-0: Celastrol
Formula:C29H38O4
InChI:InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
InChI key:InChIKey=KQJSQWZMSAGSHN-JJWQIEBTSA-N
SMILES:C[C@@]12[C@](C)([C@]3([C@@](C)(CC1)CC[C@](C(O)=O)(C)C3)[H])CC[C@]4(C)C2=CC=C5C4=CC(=O)C(O)=C5C
Synonyms:- (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid
- (2R,4aS,6aS,6aR,14aS,14bR)-10-Hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
- (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid
- 2-Picenecarboxylic acid, 1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-, (2R,4aS,6aS,12bR,14aS,14bR)-
- 2-Picenecarboxylic acid, 1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-, [2R-(2α,4aβ,6aβ,12bβ,14aα,14bβ)]-
- 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, (9β,13α,14β,20α)-
- 24-Nor-D:A-friedooleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-
- D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, (20α)-
- NSC 70931
- Tripterin
- Ui1590
- See more synonyms
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Found 10 products.
Celastrol
CAS:CelastrolFormula:C29H38O4Purity:By hplc: 100% (Typical Value in Batch COA)Color and Shape: red powderMolecular weight:450.61g/molCelastrol
CAS:Carboxylic acid with additional oxygen functionsFormula:C29H38O4Purity:≥ 95.0 % (HPLC)Color and Shape:CrystallineMolecular weight:450.62Celastrol
CAS:Formula:C29H38O4Purity:≥ 98.0%Color and Shape:Red to dark red powderMolecular weight:450.61Celastrol
CAS:Controlled ProductApplications An antioxidant natural product which inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression. Used for clinical treatment for rheumatoid arthritis, was demonstrated to have antiangiogenic activity, and be inhibitory against mice tumor growth by a few recent studies. Celastrol also has been shown to have the power to kill tumor cells and can work as an anticarcinogen. Celastrol is also a leptin sensitizer with the potential to reduce weight in obesity (see W499200). References Senger, D., et al.: Science, 219, 983 (1983), Folkman, J., et al.: Nature, 1, 27 (1995), He, W., et al.: Bioorg. Med. Chem. Lett., 8, 3659 (1998), Grosios, K., et al.: Inflamm. Res., 53, 133 (2004), Yang, H., et al.: Cancer Res., 66, 4758 (2006); AAPS Newsmagazine p. 17, July 2016; Chem. and Eng. News p. 6, Aug. 8, 2016Formula:C29H38O4Color and Shape:NeatMolecular weight:450.61Celastrol
CAS:Formula:C29H38O4Purity:>98.0%(HPLC)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:450.62Celastrol
CAS:Controlled ProductHSP90 inhibitor; topoisomerase II inhibitor; anti-inflammatory; antioxidantFormula:C29H38O4Purity:Min. 95%Color and Shape:Red PowderMolecular weight:450.61 g/molTripterin
CAS:Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.Formula:C29H38O4Purity:98.56% - 99.8%Color and Shape:Red Crystalline PowderMolecular weight:450.61
