CAS 3432-99-3: 5,10-Methylene-5,6,7,8-tetrahydrofolic acid
Formula:C20H23N7O6
InChI:InChI=1S/C20H23N7O6/c21-20-24-16-15(18(31)25-20)27-9-26(8-12(27)7-22-16)11-3-1-10(2-4-11)17(30)23-13(19(32)33)5-6-14(28)29/h1-4,12-13H,5-9H2,(H,23,30)(H,28,29)(H,32,33)(H4,21,22,24,25,31)/t12?,13-/m0/s1
InChI key:InChIKey=QYNUQALWYRSVHF-ABLWVSNPSA-N
SMILES:O=C1C=2N3C(CN(C3)C4=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C4)(CNC2NC(N)=N1)[H]
Synonyms:- (+)-5,10-Methylene-5,6,7,8-tetrahydrofolic acid
- (2s)-2-(4-(3-Amino-1-oxo-5,6,6a,7-tetrahydroimidazo[1,5-f]pteridin-8(1H,4H,9H)-yl)benzamido)pentanedioic acid
- 5,10-Methylene-(6RS)-tetrahydrofolic acid
- 5,10-Methylenetetrafolate
- 5,10-Methylenetetrahydrofolic acid
- <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-
- Anx-510
- Folic acid, tetrahydro-N<sup>5</sup>,N<sup>10</sup>-methylene-
- Folitixorin
- Glutamic acid, N-[p-(3-amino-5,6,6a,7-tetrahydro-1-hydroxyimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-, <span class="text-smallcaps">L</span>-
- Imidazo[1,5-f]pteridine, <span class="text-smallcaps">L</span>-glutamic acid deriv.
- See more synonyms
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Found 8 products.
Folitixorin (~80%) (Mixture of Diastereomers)
CAS:Stability Hygroscopic, Moisture Sensitive, Temperature Sensitive Applications A stable folate lyophilized compound suitable for use in the treatment of cancer and other therapies. References Park, H., et al.: Science, 268, 1866 (1995), Banerjee, R., et al.: J. Biol. Chem., 282, 14916 (2007), Klar, T., et al.: J. Mol. Biol., 366, 954 (2007),Formula:C20H23N7O6Color and Shape:NeatMolecular weight:457.445,10-methylenetetrahydrofolate
CAS:Formula:C20H23N7O6Purity:95%Color and Shape:SolidMolecular weight:457.4399Calcium Folinate EP Impurity I (Folitixorin) (Mixture of Diastereomers)
CAS:Formula:C20H23N7O6Molecular weight:457.45Folitixorin-d4 Disodium Salt (>80%) (Mixture of Diastereomers)
CAS:Controlled ProductFormula:C20H17D4N7Na2O6Color and Shape:NeatMolecular weight:505.43Folitixorin
CAS:ANX-510: folate-derived; enhances FdUMP, inhibits thymidylate synthase, depletes TTP, and kills tumor cells.Formula:C20H23N7O6Color and Shape:SolidMolecular weight:457.445,10-Methylene-5,6,7,8-tetrahydrofolic acid - mixture of diastereomers
CAS:5,10-Methylene-5,6,7,8-tetrahydrofolic acid is a molecule that is found in cells. It is an essential cofactor for many biological processes. The folate form of 5,10-methylene-5,6,7,8-tetrahydrofolic acid (5MTHF) can be synthesized by the enzyme methylenetetrahydrofolate reductase. This enzyme uses N5,N10-methenyltetrahydrofolate as a substrate and converts it to 5MTHF. The enzyme activity of methylenetetrahydrofolate reductase can be inhibited by methotrexate. In this case 5MTHF will not be produced and the body's supply of folate will decrease. The structural analysis of 5MTHF has been performed using titration calorimetry and x-ray crystallography.Formula:C20H23N7O6Purity:80%MinColor and Shape:PowderMolecular weight:457.44 g/molRef: 4Z-F-068024
Discontinued product
