CAS 34632-04-7: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2S)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)-

L-Cephalexin is a beta-lactam antibiotic that inhibits the synthesis of peptidoglycan. L-Cephalexin binds to the penicillin-binding proteins in the bacterial cell wall by competitive inhibition. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. L-Cephalexin has been shown to be effective against streptococcal pharyngitis caused by Streptococcus pyogenes and other bacteria. The optimum concentration for L-Cephalexin is 0.5mg/ml, which can be achieved through a control analysis.

Stability Hygroscopic Applications The L-diastereomer of the β-lactam antibiotic Cephalexin (C256800). It is transported by PEPT1 (the oligopeptide transporter responsible for absorption of peptide nutrients in the small intestine) with high affinity, but is not metabolized by PEPT1 itself. References Mitsuoka, K. et al.: Biol. Pharmac. Bull., 32, 1459 (2009); Snyder, N.J. et al.: Antimicrob. Agents Chemother., 41, 1649 (1997);