Benzo[b]thiophene, 7-fluoro- (9CI) is an organic compound characterized by its fused ring structure, which includes a benzene ring and a thiophene ring. The presence of a fluorine atom at the 7-position of the benzo[b]thiophene framework introduces unique electronic and steric properties, potentially influencing its reactivity and interactions with biological systems. This compound is typically a pale yellow to brown solid and is soluble in organic solvents. It may exhibit interesting photophysical properties, making it of interest in various applications, including organic electronics and materials science. The fluorine substitution can enhance lipophilicity and alter the compound's biological activity, which is relevant in medicinal chemistry. As with many heterocyclic compounds, benzo[b]thiophene derivatives can participate in various chemical reactions, including electrophilic substitutions and nucleophilic additions. Safety data should be consulted for handling and usage, as with all chemical substances, to ensure proper precautions are taken.

Benzo[b]thiophene, 7-fluoro- (9CI)

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7-Fluorobenzo[b]thiophene

7-Fluoro-1-benzothiophene is an inhibitor of class I and II histone deacetylases (HDACs) that is used in the treatment of cancer. It binds to the active site of HDACs, inhibiting their activity and preventing the deacetylation of lysine residues on histones. 7-Fluoro-1-benzothiophene has been shown to inhibit tumor growth in mice, with minimal toxicity in healthy cells. The drug also exhibits a low affinity for other classes of HDACs, including class III and IV. In addition, 7-fluoro-1 benzothiophene has been shown to be selective for HDACs over other protein targets such as cyclooxygenase 2 (COX2).

CAS 346592-74-3: Benzo[b]thiophene, 7-fluoro- (9CI)

7-Fluorobenzo[b]thiophene

Ref: 10-F244841

7-Fluorobenzo[b]thiophene

Ref: IN-DA007D5O

7-Fluorobenzo[b]thiophene

Ref: 54-PC910028

7-fluoro-1-benzothiophene

Ref: 3D-FF104588