CAS 3471-05-4: Anabaseine

Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.

Natural neurotoxin

Anabaseine hydrochloride is a nicotinic acetylcholine receptor agonist, which is derived from marine worms, specifically the genus *Anabaseis*. The compound functions by binding to and activating nicotinic acetylcholine receptors (nAChRs), which are ionotropic receptors found in both the central and peripheral nervous systems. This activation results in the modulation of neurotransmitter release and can influence various neural pathways. Anabaseine hydrochloride is primarily utilized in research settings to study its effects on neural signal transmission, cognition, and behavior. Its ability to modulate nAChRs makes it a valuable tool in the investigation of neurodegenerative diseases, such as Alzheimer's, and in the exploration of potential therapeutic targets for cognitive enhancement. Scientists utilize this compound to understand nAChR-related mechanisms and to evaluate its potential as a model compound for drug development in neuropharmacology.