CAS 347841-67-2: Thymidine-a,a,a,6-d4 (9CI)

Thymidine-a,a,a,6-D4 is a nucleoside analogue that inhibits the replication of the hepatitis B virus. It is an analogue of thymidine and is activated by phosphorylation to its active form. This drug prevents viral replication by inhibiting early events in the viral life cycle. Thymidine-a,a,a,6-D4 has been shown to inhibit the synthesis of viral DNA and to inhibit the incorporation of thymidine into newly synthesized DNA. Thymidine-a,a,a,6-D4 also inhibits telbivudine resistance mutations in vitro.

Applications Thymidine-alpha,alpha,alpha,6-d4 (CAS# 347841-67-2) is a useful isotopically labeled research compound.