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CAS 348086-71-5: N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-(4-pyridin-2-ylphenyl)acetamide
Formula:C18H18N4O3S2
InChI:InChI=1S/C18H18N4O3S2/c1-12-17(27(19,24)25)26-18(21-12)22(2)16(23)11-13-6-8-14(9-7-13)15-5-3-4-10-20-15/h3-10H,11H2,1-2H3,(H2,19,24,25)
InChI key:InChIKey=IVZKZONQVYTCKC-UHFFFAOYSA-N
SMILES:N(C(CC1=CC=C(C=C1)C2=CC=CC=N2)=O)(C)C=3SC(S(N)(=O)=O)=C(C)N3
Synonyms:- Bay-57-1293
- Benzeneacetamide, N-[5-(aminosulfonyl)-4-methyl-2-thiazolyl]-N-methyl-4-(2-pyridinyl)-
- N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide
- N-[5-(Aminosulfonyl)-4-methyl-2-thiazolyl]-N-methyl-4-(2-pyridinyl)benzeneacetamide
- Pritelivir
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BAY 57-1293
CAS:BAY 57-1293 is an antiviral agent, specifically classified as a helicase-primase inhibitor. It is derived from synthetic sources, developed by Bayer. Its mode of action involves inhibiting the helicase-primase complex of the Herpes Simplex Virus (HSV), crucial for viral DNA replication. By targeting this complex, BAY 57-1293 effectively halts the replication process of the virus, thereby impeding its proliferation and infection capability. The primary application of BAY 57-1293 is in research and potential treatments aimed at Herpes Simplex Virus infections, such as HSV-1 and HSV-2. Its distinct mechanism offers a promising approach to overcoming the limitations of traditional antiviral therapies, such as those targeting viral DNA polymerase. The inhibition of the helicase-primase complex represents a strategic point of intervention, which may lead to enhanced efficacy in antiviral drug development. This makes it a significant focus for research aimed at developing more effective treatments for HSV-related conditions.Formula:C18H18N4O3S2Purity:Min. 95%Molecular weight:402.49 g/molN-Methyl-N-(4-Methyl-5-Sulfamoylthiazol-2-Yl)-2-(4-(Pyridin-2-Yl)Phenyl)Acetamide
CAS:N-Methyl-N-(4-Methyl-5-Sulfamoylthiazol-2-Yl)-2-(4-(Pyridin-2-Yl)Phenyl)AcetamidePurity:95%Molecular weight:402.49g/molBAY-57-1293
CAS:Formula:C18H18N4O3S2Purity:95%Color and Shape:SolidMolecular weight:402.4905199999999Pritelivir
CAS:Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Formula:C18H18N4O3S2Purity:97.96% - 99.42%Color and Shape:SolidMolecular weight:402.49