CAS 34893-92-0: 3,5-Dichlorophenyl isocyanate

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

3,5-Dichlorophenyl isocyanate is a chemical compound that reacts with urea and alanine to form the monoclonal antibody for the treatment of diabetic patients. It has been shown to have mesomeric properties. 3,5-Dichlorophenyl isocyanate reacts with hydrochloric acid to form an enantiomer in the reaction solution. The lc-ms/ms method can be used to identify this enantiomer by measuring its nmr spectra and magnetic resonance spectroscopy. 3,5-Dichlorophenyl isocyanate also has low energy nuclear magnetic resonance (NMR) properties that are well suited for magnetic particles. Magnetic resonance imaging (MRI) can be used to observe these properties in vivo.

Applications 1,3-Dichloro-5-isocyanatobenzene is a reagent used in the synthesis of carbamate and aryl ether substituted pyrazinones as corticotropin releasing factor-1 receptor antagonists as well as the synthesis of novel triazolor pyridine derivatives. References Ahuja, V. et al.: Bioorg. Med. Chem. Lett., Zhang, L. et al.: Turk. J. Chem., 39, 876 (2015);

3,5-Dichlorophenyl isocyanate is used as an intermediate for medicine and in iprodione. It is also useful for proteomic research. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.