CAS: 351424-20-9

TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.

CBA is a reactive intermediate that is formed by the conjugation of two molecules. It has been shown to be cytotoxic and to have anti-viral effects in vitro. CBA has also been shown to be an effective treatment for lymphocytic leukemia in mice. It was found that CBA was able to inhibit the proliferation of virus-infected cells and to reduce the production of virus progeny. Moreover, it has been shown that CBA can bind to cation channels and linear model systems, thus inhibiting the flow of ions across cell membranes. The most likely mechanism for CBA's antiviral activity is its ability to interfere with viral DNA replication or RNA synthesis, which may be due to its ability to react with nucleic acids.

TRPM4-IN-1