CAS: 352020-03-2

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Stresscopin is a specific ligand for the corticotropin-releasing hormone receptor type 2 (CRHR2). Transcripts are expressed in brain and most tissues analyzed. Intraperitoneal injections of stresscopin suppresses heat-induced edema formation in anesthetized rats. It also decreases food intake and exhibits an inhibitory effect on gastric emptying activity. This CRHR2 agonist might represent an endogenous ligand for maintaining homeostasis after stress.

Stresscopin is a peptide that belongs to the family of activators. It is a molecular "switch" that can be used to control the activity of ion channels and protein interactions. Stresscopin is purified from human tissue and is supplied as lyophilized powder.