CAS 35356-70-8: Methyl 2-acetamidoacrylate

Methyl 2-acetamidoacrylate is an amine that is used to synthesize dyes, pharmaceuticals, and agrochemicals. It is a white solid with a low melting point that can be dissolved in water or methanol. Methyl 2-acetamidoacrylate is also used as a reactant in the synthesis of other compounds. This compound has been shown to inhibit bacterial translocation in vivo in CD-1 mice. The reaction solution of methyl 2-acetamidoacrylate has been studied using acid analysis and NMR spectroscopy for kinetic data. Methyl 2-acetamidoacrylate can be synthesized from two different starting materials: 2-aminoisobutyric acid or sodium carbonate. The asymmetric synthesis of methyl 2-acetamidoacrylate uses protonation to produce the desired enantiomeric form of the product.

Methyl 2-acetamidoacrylate

Applications Methyl 2-acetamidoacrylate is an ethyl pyruvate analog that exhibits anti-inflammatory properties and has also been shown to decrease sepsis-induced acute kidney injury in mice. References Leelahavanichkul, A., et al: Am. J. Physiol.-Renal, 295, F1825 (2008)

Methyl 2-acetamidoacrylate exhibits anti-inflammatory property and decreases induced acute kidney injury in mice. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.