CAS 3569-21-9: Indole-3-propanol

3-(3-Hydroxypropyl)-1H-indole

Indole-3-propanol is a reversible inhibitor of the enzyme dihydrofolate reductase that blocks the synthesis of purine nucleotides. It has been shown to have a regulatory effect on bacterial growth and may be used as an antimicrobial agent. Indole-3-propanol is an inhibitor of the enzyme dihydrofolate reductase, which catalyzes the reduction of dihydrofolic acid to tetrahydrofolic acid. This conversion is essential for DNA synthesis and repair in bacteria. Indole-3-propanol inhibits this reaction reversibly by binding to the hydroxy group in the active site of the enzyme, thereby blocking access to substrate analogues such as phosphoribosyl pyrophosphate (PRPP). The compound also inhibits human serum proteins, such as albumin, which are involved in metabolizing drugs. Molecular modeling studies suggest that indole-3-propanol binds to two l

Indole-3-propanol is a chemical compound that belongs to the group of indole derivatives. It is an organic compound that is used in the synthesis of fine chemicals, research chemicals, and reagents. It can be used as a building block for various compounds and has been used in the synthesis of pharmaceuticals such as deferiprone. Indole-3-propanol has been shown to be useful as a versatile building block for complex compounds with interesting properties. It can also be used as an intermediate for other chemical reactions or as a scaffold for drug design.