
CAS 35730-78-0: Cynaropicrin
Formula:C19H22O6
InChI:InChI=1S/C19H22O6/c1-8-5-14(24-18(22)9(2)7-20)16-11(4)19(23)25-17(16)15-10(3)13(21)6-12(8)15/h12-17,20-21H,1-7H2/t12-,13-,14-,15-,16+,17+/m0/s1
InChI key:InChIKey=KHSCYOFDKADJDJ-NQLMQOPMSA-N
SMILES:C=C1[C@@]2([C@@]3([C@@]([C@@H](OC(C(CO)=C)=O)CC(=C)[C@@]2(C[C@@H]1O)[H])(C(=C)C(=O)O3)[H])[H])[H]
Synonyms:- 2-(Hydroxymethyl)-2-propenoic Acid (3aR,4S,6aR,8S,9aR,9bR)-Dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl Ester
- 2-Propenoic acid, 2-(hydroxymethyl)-, (3aR,4S,6aR,8S,9aR,9bR)-dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno(4,5-b)furan-4-yl ester
- 2-Propenoic acid, 2-(hydroxymethyl)-, dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester, [3aR-(3aα,4α,6aα,8β,9aα,9bβ)]-
- 68370-45-6
- Azuleno[4,5-b]furan, 2-propenoic acid deriv.
- Cynaropicrin
- Cynaropikrin
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Cynaropicrin
CAS:Cynaropicrin is a sesquiterpene lactone found in artichoke with anti-hepatitis C and trypanosome activity and inhibits NF-κB activation.Formula:C19H22O6Purity:96.15%Color and Shape:SolidMolecular weight:346.37Cynaropicrin
CAS:Cynaropicrin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Formula:C19H22O6Purity:(HPLC) ≥95%Color and Shape:PowderMolecular weight:346.38Cynaropicrin
CAS:Cynaropicrin is a potent activator of the AhR-Nrf2-Nqo1 pathway, and could therefore be applied to prevention of UVB-induced photo aging; it may be a potential anticancer agent against some leukocyte cancer cells such as lymphoma or leukemia, through pro-apoptotic activity. Cynaropicrin shows in vivo activity against Trypanosoma brucei. Cynaropicrin possesses immunomodulatory effects on cytokine release, nitric oxide production and immunosuppressive effects. Cynaropicrin also has anti-inflammatory effects, it may participate in the inflammatory response by inhibiting the production of inflammatory mediators and the proliferation of lymphocytes and its inhibitory effect is mediated through conjugation with sulphydryl groups of target protein(s).Formula:C19H22O6Purity:95%~99%Molecular weight:346.379Cynaropicrin - Cynara cardunculus (artichoke)
CAS:Cynaropicrin is a sesquiterpene lactone, which is a bioactive compound derived from Cynara cardunculus, commonly known as the artichoke. The source of this compound is primarily the leaves and flowering parts of the plant, which have been traditionally used in herbal medicine. Cynaropicrin exhibits its biological activity through the inhibition of various inflammatory pathways, particularly by modulating the NF-κB signaling pathway, which is crucial in the regulation of immune response and inflammation. Cynaropicrin has been the subject of scientific studies due to its potential therapeutic applications. It shows promise in the treatment of inflammatory conditions and has been investigated for its hepatoprotective properties, suggesting a role in liver health. Additionally, its antioxidant effects may contribute to overall cellular protection. Research continues to explore its utility in pharmacological contexts, aiming to substantiate its efficacy and safety across different applications. This compound serves as a compelling target for further research in the development of natural anti-inflammatory agents.Formula:C19H22O6Purity:Min. 95%Color and Shape:PowderMolecular weight:346.37 g/molCynaropicrin
CAS:LactoneFormula:C19H22O6Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:346.38Cynaropicrin
CAS:Formula:C19H22O6Purity:≥ 97.0%Color and Shape:White to beige powderMolecular weight:346.38