1,3-Thiazole-4-carboxamide is a heterocyclic organic compound characterized by a five-membered ring containing both sulfur and nitrogen atoms. The thiazole ring structure contributes to its unique chemical properties, including its ability to participate in various chemical reactions. This compound features a carboxamide functional group, which enhances its solubility in polar solvents and can influence its biological activity. Typically, 1,3-thiazole derivatives exhibit a range of pharmacological properties, making them of interest in medicinal chemistry. The presence of the carboxamide group may also contribute to hydrogen bonding capabilities, affecting its interactions with biological targets. Additionally, this compound may be synthesized through various methods, including cyclization reactions involving appropriate precursors. Its applications can span from agricultural chemicals to pharmaceuticals, depending on the specific derivatives and modifications made to the thiazole structure. Overall, 1,3-thiazole-4-carboxamide is a versatile compound with significant potential in various chemical and biological applications.

1,3-thiazole-4-carboxamide

3575-09-5: 4-Thiazolecarboxamide, 1,3-Thiazole-4-carboxamide

THIAZOLE-4-CARBOXAMIDE

Thiazole-4-carboxamide

Thiazole-4-carboxamide is a potent antagonist of the human 5HT2B receptor. It also has minimal toxicity and is selective for the 5HT2B receptor. Thiazole-4-carboxamide has been shown to be cytotoxic to lung fibroblasts in vitro, with significant cell death observed after 72 hours. The cytotoxicity of thiazole-4-carboxamide may be due to its ability to inhibit adenine nucleotide synthesis and uptake in cells, leading to the depletion of ATP. This drug may also lead to cancer cell death by inhibiting protein synthesis and glycosidic bond formation.
Clinical studies suggest that this drug may be effective against a variety of cancers including breast, prostate, and colorectal cancer.

1,3-Thiazole-4-carboxamide

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CAS 3575-09-5: 1,3-thiazole-4-carboxamide

THIAZOLE-4-CARBOXAMIDE

Ref: IN-DA00C0Y8

Thiazole-4-carboxamide

Ref: 10-F223374

Thiazole-4-carboxamide

Ref: 3D-FT52217

1,3-Thiazole-4-carboxamide

Ref: 54-OR59344

1,3-Thiazole-4-carboxamide

Ref: 3D-DAA57509