CAS 362-06-1: 2-Hydroxyestrone
Formula:C18H22O3
InChI:InChI=1S/C18H22O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,19-20H,2-7H2,1H3/t11-,12+,14-,18-/m0/s1
InChI key:InChIKey=SWINWPBPEKHUOD-JPVZDGGYSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=C(O)C4)(CC1)[H])[H])(CCC2=O)[H]
Synonyms:- 2,3-Dihydroxyestra-1(10),2,4-Trien-17-One
- 2,3-Dihydroxyestra-1,3,5(10)-trien-17-one
- Catecholestrone
- Ccris 9276
- Estra-1,3,5(1)-trien-17-one, 2,3-dihydroxy-
- Estra-1,3,5(10)-trien-17-one, 2,3-dihydroxy-
- 2-Hydroxyestrone
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Found 6 products.
2-Hydroxyestrone 100 µg/mL in Acetonitrile
CAS:Formula:C18H22O3Color and Shape:Single SolutionMolecular weight:286.372-Hydroxy estrone
CAS:Controlled Product2-Hydroxy estrone is a metabolite of estradiol. It has been shown to be involved in the development of breast cancer and may be a biomarker for the disease. 2-Hydroxy estrone has been found to have genotoxic effects in experimental models and may cause DNA damage. It is also thought to play a role in regulating body weight, reproductive function, mood, and cognition. 2-Hydroxy estrone is an estrogen precursor that binds catechol-o-methyltransferase (COMT) and thereby inhibits COMT activity. This leads to increased levels of dopamine which contributes to breast cancer development. Experimental models have shown that 2-hydroxy estrone can induce tumours in mice by binding to estrogen receptors and stimulating cell division.Formula:C18H22O3Purity:Min. 95%Color and Shape:PowderMolecular weight:286.37 g/mol2-Hydroxy Estrone
CAS:Controlled ProductFormula:C18H22O3Color and Shape:Off-White To Light BrownMolecular weight:286.37
