Ethyl 2-fluoro-4-nitrobenzoate is an organic compound characterized by its ester functional group, specifically derived from benzoic acid. It features a fluoro group and a nitro group positioned on the aromatic ring, which significantly influence its chemical properties and reactivity. The presence of the nitro group typically enhances the compound's electrophilicity, making it more reactive in nucleophilic substitution reactions. Ethyl 2-fluoro-4-nitrobenzoate is generally a colorless to pale yellow liquid or solid, depending on its purity and form. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water due to its hydrophobic aromatic structure. This compound is often used in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals, owing to its ability to participate in various chemical reactions, including nucleophilic aromatic substitution and coupling reactions. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested.

ethyl 2-fluoro-4-nitrobenzoate

363-32-6: Benzoic Acid, 2-Fluoro-4-Nitro-, Ethyl Ester

Ethyl 2-fluoro-4-nitrobenzoate

Apalutamide Impurity 21

Ethyl 2-fluoro-4-nitrobenzoate is a selective inhibitor of the isoform PI3K δ. It has been shown to inhibit cell proliferation and tumor growth in xenograft models, as well as inhibiting cancer cell proliferation in vitro. This drug is being developed for the treatment of cancer, with intraperitoneal administration being the most likely route. The optimal structure of this compound is still being investigated and it is unknown whether substituents on the phenyl ring are necessary for activity.

CAS 363-32-6: ethyl 2-fluoro-4-nitrobenzoate

Ethyl 2-fluoro-4-nitrobenzoate

Ref: 10-F337155

Ethyl 2-fluoro-4-nitrobenzoate

Ref: 54-PC103843

Ethyl 2-fluoro-4-nitrobenzoate

Ref: IN-DA007A4O

Apalutamide Impurity 21

Ref: ST-EA-CP-A92029

Ethyl 2-Fluoro-4-Nitrobenzoate

Ref: 3D-FE79489