CAS 363-72-4: Pentafluorobenzene

Pentafluorobenzene is a fluorinated benzene with anesthetic properties. Pentafluorobenzene has been shown to potently and reversibly inhibited human α4β2 neuronal nicotinic acetylcholine receptor depe ndent on drug hydrophobicity in Xenopus laevis oocyte. New reaction conditions are described that enable the direct arylation of pentafluorobenzene with sterically encumbered aryl bromides and aryl chlorides. Bis (pentafluoropheny1) methane and tris (pentafluoropheny1) methane were prepared in 77 and 92% yields, respectively, by a Friedel-Crafts reaction of pentafluorobenzene with methylene chloride and chloroform using aluminum chloride as the Lewis acid.This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Pentafluorobenzene is a reactive molecule that is a hybridized and kinetic data. It is classified as an organometallic compound, which are compounds that contain metal atoms. Pentafluorobenzene has been shown to bind with copper chloride, which is a nucleophilic substitution reaction. The activation energies for this reaction were found to be -0.6 and -1.2 kcal/mol respectively. This molecule also reacts with trifluoroacetic acid, hydrogen fluoride, and dipropyl ether to form the corresponding fluorinated products. Pentafluorobenzene has shown anti-inflammatory properties in rats with inflammatory diseases by inhibiting the production of prostaglandins in the body. It may also have anti-inflammatory effects in people with autoimmune diseases due to its ability to inhibit the production of prostaglandins as well as transfer reactions where it binds with copper chloride, which can cause inflammation in people with autoimmune disorders

Pentafluorobenzene, 99%

Pentafluorobenzene