CAS 3648-21-3: Diheptyl phthalate

Di-n-heptyl Phthalate is a Phthalate derivative and an organic extract contaminant found in drinking water, which was shown to activate Nrf-2-Mediated Antioxidant response in human cell line. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications Di-n-heptyl Phthalate is a Phthalate derivative and an organic extract contaminant found in drinking water, which was shown to activate Nrf-2-Mediated Antioxidant response in human cell line. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Wang, S., et al.: Environ. Sci. Technol., 47, 4768 (2013);

Di-n-heptyl Phthalate (DHP) is a phthalate. It is a reactive compound that can be used as a polymerization catalyst and a surface methodology. DHP has been shown to have low toxicity in mice, with the highest toxicity seen at doses of 1000 mg/kg body weight. The hydroxyl group on the molecule reacts with sodium carbonate, which causes it to form sodium salts of DHP. These salts are then hydrolyzed by glucuronidase in the liver, resulting in DHP being released back into the bloodstream. The acetate extract from DHP is toxic to CD-1 mice at doses greater than 1 mg/kg body weight.