6-Chloro-3,4-dihydro-2H-chromene is an organic compound characterized by its chromene structure, which consists of a benzene ring fused to a pyran ring. The presence of a chlorine atom at the 6-position contributes to its unique reactivity and properties. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and form. It is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its ability to interact with biological targets. The dihydro form indicates that it has two hydrogen atoms added to the chromene structure, which can influence its stability and reactivity. Additionally, 6-chloro-3,4-dihydro-2H-chromene may exhibit various functional properties, including fluorescence and the ability to participate in electrophilic aromatic substitution reactions. Its solubility can vary based on the solvent used, and it is important to handle this compound with care, following appropriate safety protocols due to the presence of chlorine.

6-chloro-3,4-dihydro-2H-chromene

3722-71-2: 2H-1-benzopyran, 6-chloro-3,4-dihydro-, 6-Chlorochromane

6-Chloro-3,4-dihydro-2H-1-benzopyran is a cytostatic agent that inhibits the growth of cancer cells by interfering with the synthesis of DNA and RNA. It has been shown to have an anticancer activity in glioblastoma cells and an analog of 6-chloro-3,4-dihydro-2H-1-benzopyran has been shown to have anticancer activity in vitro. The mechanism of action involves inhibition of cholesterol biosynthesis which leads to decreased production of lipoproteins, which are needed for cell growth. This drug also inhibits the enzyme HMG CoA reductase, which is involved in the synthesis of cholesterol. In addition, 6CHMBP has been found to have growth inhibitory effects on Sprague Dawley rats and cyclic AMP levels were increased in these animals.

CAS 3722-71-2: 6-chloro-3,4-dihydro-2H-chromene

6-Chloro-3,4-dihydro-2H-1-benzopyran

Ref: 3D-DAA72271

6-chlorochroman

Ref: 10-F362413

6-Chloro-3,4-dihydro-2H-1-benzopyran

Ref: 54-OR77724