
CAS 37318-06-2: Elaiophylin
Formula:C54H88O18
InChI:InChI=1/C54H88O18/c1-13-37-33(9)71-53(63,25-41(37)67-45-23-39(55)49(61)35(11)65-45)31(7)47(59)29(5)51-27(3)19-15-17-22-44(58)70-52(28(4)20-16-18-21-43(57)69-51)30(6)48(60)32(8)54(64)26-42(38(14-2)34(10)72-54)68-46-24-40(56)50(62)36(12)66-46/h15-22,27-42,45-52,55-56,59-64H,13-14,23-26H2,1-12H3/b19-15+,20-16+,21-18+,22-17+/t27-,28-,29-,30-,31-,32-,33+,34+,35-,36-,37+,38+,39-,40-,41+,42+,45-,46-,47+,48+,49+,50+,51-,52-,53+,54+/m0/s1
InChI key:InChIKey=OSERMIPXNLXAPD-MJMYBOKFSA-N
SMILES:O([C@H]1[C@H](CC)[C@@H](C)O[C@]([C@H]([C@@H]([C@H](C)[C@@]2([C@@H](C)/C=C/C=C/C(=O)O[C@]([C@H]([C@H]([C@H](C)[C@@]3(O)C[C@@H](O[C@H]4C[C@H](O)[C@H](O)[C@H](C)O4)[C@H](CC)[C@@H](C)O3)O)C)([C@@H](C)\C=C\C=C\C(=O)O2)[H])[H])O)C)(O)C1)[C@H]5C[C@H](O)[C@H](O)[C@H](C)O5
Synonyms:- 1,9-Dioxacyclohexadeca-3,5,11,13-tetraene-2,10-dione, 8,16-bis[3-[4-[(2,6-dideoxy-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl)oxy]-5-ethyltetrahydro-2-hydroxy-6-methyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-7,15-dimethyl-, [7S-[3E,5E,7R*,8R*[1R*,2S*,3R*(2S*,4S*,5S*,6S*)],11E,13E,15R*,16R*[1R*,2S*,3R*(2S*,4S*,5S*,6S*)]]]-
- 1,9-Dioxacyclohexadecane, elaiophylin deriv.
- 5001B
- Antibiotic 5001B
- Antibiotic 56-62
- Antibiotic A 164AB
- Azalomycin B
- Efomycin E
- Efomycine E
- Elaiophylin
- Gopalamicin
- See more synonyms
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Found 4 products.
Elaiophylin
CAS:Elaiophylin is a potent antitumor agent with an elaiophylin-binding site. It has been shown to have potent antitumor activity in a model system and to inhibit the growth of tumor cells in vitro and in vivo, by binding to the receptor. Elaiophylin binds to wild-type and mutant cells at identical concentrations, but only the wild-type cells are inhibited by this binding. This inhibition leads to apoptosis in the wild-type cells, but not in the mutant cells. Elaiophylin also inhibits cellular proliferation through transcriptional regulation by inhibiting DNA synthesis. The chemical structure of elaiophylin is similar to that of epidermal growth factor (EGF).Formula:C54H88O18Purity:Min. 95%Molecular weight:1,025.27 g/molRef: 3D-FE168603
Discontinued productElaiophylin (>85%)
CAS:Applications Elaiophylin is a macrolide antibiotic with immunosuppresive activity.Formula:C54H88O18Purity:>85%Color and Shape:NeatMolecular weight:1025.27Elaiophylin
CAS:Elaiophylin exhibits anti-Plasmodium falciparum and anti-Trypanosoma brucei activity; IC50: 0.36 μM & 0.45 μM, respectively.Formula:C54H88O18Purity:98%Color and Shape:SolidMolecular weight:1025.27